49ers | Jimmy Garoppolo placed on IR

San Francisco 49ers QB Jimmy Garoppolo (knee) was placed on the Reserve/Injured list Wednesday, Sept. 26.

Footballguys View: Just a procedural move that was expected as Garoppolo is done for the year. The 49ers now turn to C.J. Beathard as their starting quarterback. Nick Mullens was signed to the active roster from the practice squad in a corresponding move.

Bills | LeSean McCoy has limited practice

Buffalo Bills RB LeSean McCoy (rib) was limited in practice Wednesday, Sept. 26.

Footballguys View: McCoy wasn’t on the field for the game against the Vikings last Sunday, but he says he’s going to be out there in Week 4. Rib injuries largely come down to pain management. Being limited on Wednesday is a positive sign, but we’ll see if he can practice fully on Friday. The Bills travel to play the Packers on Sunday.