Philadelphia Eagles LB Duke Riley (biceps), TE Richard Rodgers (ankle), CB Kevon Seymour (knee) and DE Josh Sweat (wrist) did not participate in practice Friday, Dec. 25, and have been ruled out for Week 16. DT Fletcher Cox (neck) did not practice and is listed as questionable. DE Derek Barnett (calf) was limited during practice and is listed as questionable. P Cameron Johnston (concussion) fully participated in practice but is listed as questionable. CB Grayland Arnold (hamstring), RB Jason Huntley (illness) and CB Darius Slay (concussion) fully participated in practice and are not on the injury report.

Philadelphia Eagles WR Jalen Reagor (ankle) fully participated in practice Friday, Dec. 25, and is not on the injury report for Week 16.

Footballguys View: Reagor is worth a what-the-heck flex look this week with Jalen Hurts heating up as a passer and the Cowboys defense one of the best matchups for fantasy in the league this year.

Indianapolis Colts DL Denico Autry (rest), TE Trey Burton (rest), DE Justin Houston (rest), OG Quenton Nelson (back) and TE Jack Doyle (quad) fully practiced Friday, Dec. 25, and are not on the injury report. DE Kemoko Turay (rest), S Julian Blackmon (rest), LB Darius Leonard (rest), CB Kenny Moore II (rest) and TE Mo Alie-Cox (knee) did not practice and are not on the injury report. DT DeForest Buckner (ankle) was limited in practice and does not carry an injury designation. OT Anthony Castonzo (knee, ankle) did not practice and is questionable, while DE Al-Quadin Muhammad (ankle) fully practiced and is questionable. OT Braden Smith (illness) was placed on the Reserve/COVID-19 list and has been ruled out. WR Marcus Johnson (quadriceps) has been ruled out after he did not practice.

New York Giants CB Darnay Holmes (knee) was limited during practice Friday, Dec. 25, but has been ruled out for Week 16. LB Blake Martinez (ankle) was limited during practice and is listed as questionable. OT Matt Peart (ankle) fully participated in practice and is not on the injury report.

New York Giants TE Evan Engram (calf) fully participated in practice Friday, Dec. 25, and is not on the injury report for Week 16.

Kansas City Chiefs RB Clyde Edwards-Helaire (ankle) did not practice Friday, Dec. 25, and he has been ruled out for Week 16 vs. the Atlanta Falcons.

Footballguys View: The Chiefs hope to get him back for the playoffs. Le’Veon Bell will start this week and Darrel Williams will also figure into the backfield mix. Bell is more flex play than RB2 as the Falcons defense has been stingy against running backs this year.

Buffalo Bills QB Josh Allen (knee/ankle) fully practiced Friday, Dec. 25.

Buffalo Bills DE A.J. Epenesa (non-injury related) and CB Tre’Davious White (neck) fully practiced Friday, Dec. 25. QB Jake Fromm (non-injury related), S Jaquan Johnson (ankle) WR Andre Roberts (back) and OT Daryl Williams (groin) were limited. TE Reggie Gilliam (knee/hamstring) and OT Ty Nsekhe (groin) did not practice.

Chicago Bears WR Allen Robinson (hamstring) was limited Friday, Dec. 25, and is questionable for Week 16 at the Jacksonville Jaguars.

Chicago Bears DB Deon Bush (foot), DT Akiem Hicks (ankle), DE Mario Edwards Jr. (hamstring), LB Khalil Mack (shoulder), DT Bilal Nichols (knee) and DB Duke Shelley (knee/foot) are questionable for Week 16 at the Jacksonville Jaguars after being limited Friday, Dec. 25. WR Cordarrelle Patterson (knee) did not practice and is questionable. TE Demetrius Harris (foot) was limited Friday and is doubtful. CBs Jaylon Johnson (shoulder) and Buster Skrine (concussion) did not practice and are out. S Eddie Jackson (hip) was limited and is not on the report. OL Charles Leno Jr. (toe), LB Robert Quinn (ankle), OL Jason Spriggs (thumb), LB Danny Trevathan (ankle) and LB James Vaughters (Achilles) were full participants and are not on the injury report.